Author(s):
Veerabhadrappa Mendagudli, Shivaleela S. Sarawad
Email(s):
Veerabhadrappa.bijapur@gmail.com
DOI:
10.52711/2454-2660.2026.00017 
Address:
Veerabhadrappa Mendagudli1, Shivaleela S. Sarawad2
1Principal, BLDEA’s College of Nursing, Jamkhandi, Karnataka, India.
2Assistant Professor, BLDEA’s College of Nursing, Jamkhandi, Karnataka, India.
*Corresponding Author
Published In:
Volume - 14,
Issue - 1,
Year - 2026
ABSTRACT:
Sepsis, a critical and life-threatening syndrome, arises from a dysregulated host immune response to infection, leading to organ dysfunction and high mortality. Timely recognition and evidence-based interventions are vital for improving outcomes. This article synthesizes current medical–surgical strategies—emphasizing rapid detection, aggressive fluid resuscitation, optimized antimicrobial therapy, hemodynamic stabilization, source control, and vigilant nursing surveillance—in line with Surviving Sepsis Campaign guidelines. It also highlights the collaborative contributions of nurses, physicians, pharmacists, respiratory therapists, and dietitians. Persistent challenges such as antimicrobial resistance, diagnostic delays, and resource constraints are discussed, alongside future directions including novel biomarkers, individualized care pathways, AI-powered early-warning systems, and strengthened stewardship programs. Enhanced nursing protocols and interprofessional synergy remain key to reducing sepsis-related morbidity and mortality.
Cite this article:
Veerabhadrappa Mendagudli, Shivaleela S. Sarawad. Integrated Multidisciplinary Approaches to Sepsis Management: Advancing Medical – Surgical Nursing Practice. International Journal of Nursing Education and Research. 2026;14(1):83-4. doi: 10.52711/2454-2660.2026.00017
Cite(Electronic):
Veerabhadrappa Mendagudli, Shivaleela S. Sarawad. Integrated Multidisciplinary Approaches to Sepsis Management: Advancing Medical – Surgical Nursing Practice. International Journal of Nursing Education and Research. 2026;14(1):83-4. doi: 10.52711/2454-2660.2026.00017 Available on: https://www.ijneronline.com/AbstractView.aspx?PID=2026-14-1-17
REFERENCES:
1. World Health Organization. Global report on the epidemiology and burden of sepsis. Geneva: WHO; 2020. Available from: https://www.who.int/publications/i/item/9789240010789
2. Vincent JL, Martin GS, Levy MM. Sepsis: Pathophysiology and clinical management. BMJ. 2020;370:m3368. doi:10.1136/bmj.m3368
3. Seymour CW, Liu VX, Iwashyna TJ, Brunkhorst FM, Rea TD, Scherag A, et al. Assessment of clinical criteria for sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016;315(8):762-774. doi:10.1001/jama.2016.0288
4. Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, et al. Surviving Sepsis Campaign: International guidelines for management of sepsis and septic shock: 2016. Crit Care Med. 2017;45(3):486-552. doi:10.1097/CCM.0000000000002255
5. Evans L, Rhodes A, Alhazzani W, Antonelli M, Coopersmith CM, French C, et al. Surviving Sepsis Campaign: International guidelines for management of sepsis and septic shock 2021. Intensive Care Med. 2021;47(11):1181-1247. doi:10.1007/s00134-021-06506-y